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NEW LIBRARIES

This section presents our latest library releases.

 

CHEM-X-INFINITY AND ORIBASE PHARMA RELEASE A KINASE FOCUSED LIBRARY 23/12/2013

CHEM-X-INFINITY is pleased to announce a new library focused on kinases. The original six scaffold subfamilies designed in collaboration with Oribase Pharma are known to display activities against several targets with applications in oncology.

CHEM-X-INFINITY AND PROVENCE TECHNOLOGIES RELEASE AN AZAINDOLE LIBRARY 14/05/2010

CHEM-X-INFINITY is pleased to announce a new library focused on kinases, DNA processing enzymes and GPCRs. The original azaindole scaffold could be useful for the identification of new potent series. The library was co-designed with Provence Technologies which is a company specialized in the synthesis of azaindoles.

CHEM-X-INFINITY RELEASES A PEPTIDE SURROGATE LIBRARY 17/02/2010

CHEM-X-INFINITY is pleased to announce a new library focused on proteases. Two versatile linkers have been used to synthesize compounds able to interact with serine and cysteine residues of proteins. The compounds could also have applications in GPCRs and antibiotics.

CHEM-X-INFINITY PRESENTS TWO PEPTIDOMIMETIC LIBRARIES 06/01/2010

CHEM-X-INFINITY released a new focused library centered on the linker dialkylaminoamide. This versatile linker can be found in various active molecules targeting enzymes, ion channels and GPCRs. A selection of potent peptidomimetic structures is also presented.

CHEM-X-INFINITY RELEASES A PYRAZOLE PROPIONAMIDE LIBRARY 02/12/2009

CHEM-X-INFINITY released a new focused library centered on the pyrazole propionamide scaffold. Many strategies for the synthesis of pyrazoles are described in the literature. We used an original cyclisation to obtain pyrazole propionamides that could have applications in the GPCR field and for the discovery of new NSAIDs.

CHEM-X-INFINITY RELEASES A QUINOLINE CARBOXAMIDE LIBRARY 16/10/2009

CHEM-X-INFINITY is pleased to present a new diverse library centered around the quinoline carboxamide scaffold. This small and versatile heterocycle offers many interaction possibilities with diverse receptors as peptide and amine GPCRs or ion channels. The library is a good collection for first intention screenings.

CHEM-X-INFINITY PRESENTS A DIHYDROQUINAZOLINONE LIBRARY 18/09/2009

CHEM-X-INFINITY released a new focused library centered around the dihydroquinazolinone scaffold. Using a well-known two steps connecting chemistry and diverse sets of amines and aldehydes, the compounds could be useful for the research of new diuretics, analgesics, antibiotics and anti-tumoral compounds.

CHEM-X-INFINITY PRESENTS A CNS MODEL AND A CNS LIBRARY 03/08/2009

CHEM-X-INFINITY presents its CNS model, which was developed in collaboration with Centro de Investigación Príncipe Felipe, Valencia, Spain. The model was used to propose a diverse selection of CNS predicted compounds from Chem-X-Infinity’s libraries.

CHEM-X-INFINITY PRESENTS A NEW DIVERSE LIBRARY – EXPLORA 3 22/07/2009

CHEM-X-INFINITY is pleased to present the third library of its Explora series. The Explora libraries are designed to quickly assess the relevance of new original scaffolds. Five original structures having applications in GPCRs, kinases and peptidomimetics are proposed in Explora 3.

CHEM-X-INFINITY PRESENTS A NEW NUCLEOTIDE INTERACTING LIBRARY 21/04/2009

CHEM-X-INFINITY is pleased to present an aminopyrazole carboxamide focused library. The compounds could have applications against proteins that interact with nucleotides, like kinases, phosphodiesterases and reverse transcriptases.

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